How Do GLP-1 Medications Work?

GLP-1 medications mimic a naturally occurring hormone produced in the intestinal tract known as GLP-1 (glucagon-like peptide-1). By imitating our body’s own GLP-1 hormone (also referred to as incretin hormones,) GLP-1 medications can manage type 2 diabetes by stimulating insulin release, slowing digestion, and reducing glucagon secretion. These mechanisms aid in lowering blood glucose levels and significantly contribute to weight loss.

Below is a more detailed look at how GLP-1 medications work:

GLP-1 medications are a class of drugs known as GLP-1 receptor agonists. They mimic the effects of a naturally occurring hormone in the body called glucagon-like peptide-1 (GLP-1).

GLP-1 medications signal the pancreas to release more insulin when blood sugar levels are high, helping to lower glucose levels.

They also slow down the rate at which the stomach empties, which can help you feel full longer and potentially lead to reduced food intake and weight loss.

GLP-1 medications help suppress the release of glucagon, another hormone that raises blood sugar levels.

GLP-1 agonists signal the brain to reduce appetite and decrease food intake.

In addition to managing blood sugar, GLP-1 medications may also have other benefits, including lowering blood pressure and improving hyperlipidemia (high cholesterol and high triglycerides). Some studies have shown that GLP-1 medications may reduce the risk of cardiovascular events, such as heart attacks and strokes.